Structural differences between the closely related RNA helicases, UAP56 and URH49, fashion distinct functional apo-complexes

Structural differences between the closely related RNA helicases, UAP56 and URH49, fashion distinct functional apo-complexes

Abstract mRNA export is an essential pathway for the regulation of gene expression. In humans, closely related RNA helicases, UAP56 and URH49, shape selective mRNA export pathways through the formation of distinct complexes, known as apo-TREX and apo-AREX complexes, and their subsequent remodeling i...

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Bibliographic Details
Main Authors: Ken-ichi Fujita, Misa Ito, Midori Irie, Kotaro Harada, Naoko Fujiwara, Yuya Ikeda, Hanae Yoshioka, Tomohiro Yamazaki, Masaki Kojima, Bunzo Mikami, Akila Mayeda, Seiji Masuda
Format: Article
Language:English
Published: Nature Portfolio 2024-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-44217-8

Internet

https://doi.org/10.1038/s41467-023-44217-8

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