A Small Peptide Targeting the Ligand-Induced Androgen Receptor/Filamin a Interaction Inhibits the Invasive Phenotype of Prostate Cancer Cells

A Small Peptide Targeting the Ligand-Induced Androgen Receptor/Filamin a Interaction Inhibits the Invasive Phenotype of Prostate Cancer Cells

Prostate cancer (PC) is one of the most widespread malignancies among males worldwide. The androgen receptor (AR) plays a major role in prostate cancer development and progression and is the main target of PC therapy. Nonetheless, its action is not yet fully elucidated. We report here that the AR as...

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Bibliographic Details
Main Authors: Marzia Di Donato, Pia Giovannelli, Maria Vittoria Barone, Ferdinando Auricchio, Gabriella Castoria, Antimo Migliaccio
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Cells
Subjects:
prostate cancer
androgen receptor
androgens
cell migration
spheroids
Online Access:https://www.mdpi.com/2073-4409/11/1/14

Internet

https://www.mdpi.com/2073-4409/11/1/14

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