Wilson disease: At the crossroads between genetics and epigenetics—A review of the evidence

Environmental factors, including diet, exercise, stress, and toxins, profoundly impact disease phenotypes. This review examines how Wilson disease (WD), an autosomal recessive genetic disorder, is influenced by genetic and environmental inputs. WD is caused by mutations in the copper-transporter gen...

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Bibliographic Details
Main Authors: Dorothy A. Kieffer, Valentina Medici
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2017-09-01
Series:Liver Research
Online Access:http://www.sciencedirect.com/science/article/pii/S2542568417000290