Genetics and Functional Mechanisms of STAT3 Polymorphisms in Human Tuberculosis

Signal transducer and activator of transcription-3 (STAT3) plays an important role in biological balance. Our and others previous studies implied that STAT3 had a great effect on fast-acting innate immunity against tuberculosis (TB). We hypothesized that stat3 SNP down-regulation of STAT3 leads to a...

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Bibliographic Details
Main Authors: Feifei Wang, Guixian Huang, Ling Shen, Ying Peng, Wei Sha, Zheng W. Chen, Hongbo Shen
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2021.669394/full