Effect of age and gender on serum growth differentiation factor 15 and its relationship to bone density and bone turnover

Effect of age and gender on serum growth differentiation factor 15 and its relationship to bone density and bone turnover

Senescent cells and senescence-associated secretory phenotype (SASP) proteins are involved in age-related bone loss. Growth differentiation factor 15 (GDF 15), a stress-responsive cytokine member of the transforming growth factor-β (TGF-β) superfamily, is one of the key SASP proteins. It is strongly...

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Bibliographic Details
Main Authors: Lorenza Mattia, Fatma Gossiel, Jennifer S. Walsh, Richard Eastell
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Bone Reports
Subjects:
GDF 15
Senescence
SASP protein
Aging
Bone turnover markers
Bone density
Online Access:http://www.sciencedirect.com/science/article/pii/S2352187223000244

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http://www.sciencedirect.com/science/article/pii/S2352187223000244

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