Alterations in leukocyte DNA methylome are associated to immunosuppression in severe clinical phenotypes of septic patients

Alterations in leukocyte DNA methylome are associated to immunosuppression in severe clinical phenotypes of septic patients

IntroductionSepsis patients experience a complex interplay of host pro- and anti-inflammatory processes which compromise the clinical outcome. Despite considering the latest clinical and scientific research, our comprehension of the immunosuppressive events in septic episodes remains incomplete. Add...

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Detalhes bibliográficos
Principais autores: Jesús Beltrán-García, Germán Casabó-Vallés, Rebeca Osca-Verdegal, Paula Navarrete-López, María Rodriguez-Gimillo, Elena Nacher-Sendra, Carolina Ferrando-Sánchez, Eva García-López, Federico V. Pallardó, Nieves Carbonell, Salvador Mena-Mollá, José Luis García-Giménez
Formato: Artigo
Idioma:English
Publicado em: Frontiers Media S.A. 2024-01-01
coleção:Frontiers in Immunology
Assuntos:
DNA methylation
immunosuppression
inflammation
immune system
sepsis
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1333705/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1333705/full

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