Mitochondria-specific photoactivation to monitor local sphingosine metabolism and function

Mitochondria-specific photoactivation to monitor local sphingosine metabolism and function

Photoactivation ('uncaging’) is a powerful approach for releasing bioactive small-molecules in living cells. Current uncaging methods are limited by the random distribution of caged molecules within cells. We have developed a mitochondria-specific photoactivation method, which permitted us to r...

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Bibliographic Details
Main Authors: Suihan Feng, Takeshi Harayama, Sylvie Montessuit, Fabrice PA David, Nicolas Winssinger, Jean-Claude Martinou, Howard Riezman
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-01-01
Series:eLife
Subjects:
photoactivation
sphingolipids
coumarin
mitochondria
metabolism
signaling
Online Access:https://elifesciences.org/articles/34555

Internet

https://elifesciences.org/articles/34555

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