Neuroinvasion and Neurotropism by SARS-CoV-2 Variants in the K18-hACE2 Mouse

Neuroinvasion and Neurotropism by SARS-CoV-2 Variants in the K18-hACE2 Mouse

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) not only affects the respiratory tract but also causes neurological symptoms such as loss of smell and taste, headache, fatigue or severe cerebrovascular complications. Using transgenic mice expressing human angiotensin-converting enzyme 2...

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Bibliographic Details
Main Authors: Frauke Seehusen, Jordan J. Clark, Parul Sharma, Eleanor G. Bentley, Adam Kirby, Krishanthi Subramaniam, Sabina Wunderlin-Giuliani, Grant L. Hughes, Edward I. Patterson, Benedict D. Michael, Andrew Owen, Julian A. Hiscox, James P. Stewart, Anja Kipar
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Viruses
Subjects:
Severe Acute Respiratory Syndrome Coronavirus 2
mouse model
COVID-19
encephalitis
microgliosis
influenza A virus coinfection
Online Access:https://www.mdpi.com/1999-4915/14/5/1020

Internet

https://www.mdpi.com/1999-4915/14/5/1020

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