Simple compared to covariate-constrained randomization methods in balancing baseline characteristics: a case study of randomly allocating 72 hemodialysis centers in a cluster trial

Abstract Background and aim Some parallel-group cluster-randomized trials use covariate-constrained rather than simple randomization. This is done to increase the chance of balancing the groups on cluster- and patient-level baseline characteristics. This study assessed how well two covariate-constra...

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Bibliographic Details
Main Authors: Ahmed A. Al-Jaishi, Stephanie N. Dixon, Eric McArthur, P. J. Devereaux, Lehana Thabane, Amit X. Garg
Format: Article
Language:English
Published: BMC 2021-09-01
Series:Trials
Subjects:
Online Access:https://doi.org/10.1186/s13063-021-05590-1