Engineering the viscoelasticity of gelatin methacryloyl (GelMA) hydrogels via small “dynamic bridges” to regulate BMSC behaviors for osteochondral regeneration

Engineering the viscoelasticity of gelatin methacryloyl (GelMA) hydrogels via small “dynamic bridges” to regulate BMSC behaviors for osteochondral regeneration

The dynamic extracellular matrix (ECM) constantly affects the behaviors of cells. To mimic the dynamics of ECM with controllable stiffness and energy dissipation, this study proposes a strategy in which a small molecule, 3,4-dihydroxybenzaldehyde (DB), was used as fast “dynamic bridges'’ to con...

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Bibliographic Details
Main Authors: Changjiang Liu, Qifan Yu, Zhangqin Yuan, Qianping Guo, Xiting Liao, Feng Han, Tao Feng, Guoping Liu, Runze Zhao, Zhuang Zhu, Haijiao Mao, Caihong Zhu, Bin Li
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2023-07-01
Series:Bioactive Materials
Subjects:
Viscoelastic hydrogels
Dynamic bonds
GelMA
Dissipation
Osteochondral regeneration
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X22003243

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http://www.sciencedirect.com/science/article/pii/S2452199X22003243

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