Design and evaluation of antimalarial peptides derived from prediction of short linear motifs in proteins related to erythrocyte invasion.

Design and evaluation of antimalarial peptides derived from prediction of short linear motifs in proteins related to erythrocyte invasion.

The purpose of this study was to investigate the blood stage of the malaria causing parasite, Plasmodium falciparum, to predict potential protein interactions between the parasite merozoite and the host erythrocyte and design peptides that could interrupt these predicted interactions. We screened th...

Full description

Bibliographic Details
Main Authors: Alessandra Bianchin, Angus Bell, Anthony J Chubb, Nathalie Doolan, Darren Leneghan, Ilias Stavropoulos, Denis C Shields, Catherine Mooney
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4454681?pdf=render

Internet

http://europepmc.org/articles/PMC4454681?pdf=render

Similar Items