Investigating the relationship between DNA methylation age acceleration and risk factors for Alzheimer's disease

Investigating the relationship between DNA methylation age acceleration and risk factors for Alzheimer's disease

Abstract Introduction The “epigenetic clock” is a DNA methylation–based estimate of biological age and is correlated with chronological age—the greatest risk factor for Alzheimer's disease (AD). Genetic and environmental risk factors exist for AD, several of which are potentially modifiable. In...

Full description

Bibliographic Details
Main Authors: Daniel L. McCartney, Anna J. Stevenson, Rosie M. Walker, Jude Gibson, Stewart W. Morris, Archie Campbell, Alison D. Murray, Heather C. Whalley, David J. Porteous, Andrew M. McIntosh, Kathryn L. Evans, Ian J. Deary, Riccardo E. Marioni
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring
Subjects:
DNA methylation
Epigenetic clock
Alzheimer's disease
Genetics
Generation Scotland
Online Access:https://doi.org/10.1016/j.dadm.2018.05.006

Internet

https://doi.org/10.1016/j.dadm.2018.05.006

Similar Items