Placenta-Derived Osteoprotegerin Is Required for Glucose Homeostasis in Gestational Diabetes Mellitus

Osteoprotegerin (OPG) is involved in various biological processes, including bone remodeling, vascular calcification and pancreatic β-cell function. Although some clinical studies have shown an increase in serum OPG level during pregnancy, the role of OPG in gestational diabetes mellitus (GDM) is la...

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Bibliographic Details
Main Authors: Binbin Huang, Wen Zhu, Huashan Zhao, Fa Zeng, Esther Wang, Hefei Wang, Jie Chen, Mengxia Li, Chen Huang, Lirong Ren, Jianmin Niu, Jian V. Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.563509/full