Poly(I:C) Challenge Alters Brain Expression of Oligodendroglia-Related Genes of Adult Progeny in a Mouse Model of Maternal Immune Activation

Background: Altered white matter connectivity, as evidenced by pervasive microstructural changes in myelination and axonal integrity in neuroimaging studies, has been implicated in the development of autism spectrum disorder (ASD) and related neurodevelopmental conditions such as schizophrenia. Desp...

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Bibliographic Details
Main Authors: Xiao-Fan Zhang, Ting Chen, Aifen Yan, Jia Xiao, Yong-Li Xie, Jing Yuan, Pin Chen, Anderson On-Lam Wong, Yang Zhang, Nai-Kei Wong
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fnmol.2020.00115/full