The Toxoplasma gondii effector GRA83 modulates the host’s innate immune response to regulate parasite infection

The Toxoplasma gondii effector GRA83 modulates the host’s innate immune response to regulate parasite infection

ABSTRACT Toxoplasma gondii’s propensity to infect its host and cause disease is highly dependent on its ability to modulate host cell functions. One of the strategies the parasite uses to accomplish this is via the export of effector proteins from the secretory dense granules. Dense granule (GRA) pr...

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Bibliographic Details
Main Authors: Amara C. Thind, Caroline M. Mota, Ana Paula N. Gonçalves, Jihui Sha, James A. Wohlschlegel, Tiago W. P. Mineo, Peter J. Bradley
Format: Article
Language:English
Published: American Society for Microbiology 2023-10-01
Series:mSphere
Subjects:
Toxoplasma gondii
dense granules
GRA83
GRA15
NF-κB
innate immunity
Online Access:https://journals.asm.org/doi/10.1128/msphere.00263-23

Internet

https://journals.asm.org/doi/10.1128/msphere.00263-23

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