Silencing Formin-like 2 inhibits growth and metastasis of gastric cancer cells through suppressing internalization of integrins

Silencing Formin-like 2 inhibits growth and metastasis of gastric cancer cells through suppressing internalization of integrins

Abstract Background Formin-like 2 (FMNL2) is a member of Formin family which governs cytokinesis, cellular polarity and morphogenesis. Dysregulation of FMNL2 has been discovered in cancers and is closely related to cancers. However, the role of FMNL2 in gastric cancer remains unclear. In this study,...

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Bibliographic Details
Main Authors: Banghua Zhong, Kewei Wang, Hao Xu, Fanmin Kong
Format: Article
Language:English
Published: BMC 2018-06-01
Series:Cancer Cell International
Subjects:
Apoptosis
Formin-like 2
Gastric cancer
Integrin internalization
Invasion
Migration
Online Access:http://link.springer.com/article/10.1186/s12935-018-0576-1

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http://link.springer.com/article/10.1186/s12935-018-0576-1

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