Chicken DDX1 Acts as an RNA Sensor to Mediate IFN-β Signaling Pathway Activation in Antiviral Innate Immunity

Chicken DDX1 Acts as an RNA Sensor to Mediate IFN-β Signaling Pathway Activation in Antiviral Innate Immunity

Chickens are the natural host of Newcastle disease virus (NDV) and avian influenza virus (AIV). The discovery that the RIG-I gene, the primary RNA virus pattern recognition receptor (PRR) in mammals, is naturally absent in chickens has directed attention to studies of chicken RNA PRRs and their func...

Full description

Bibliographic Details
Main Authors: Zhenyu Lin, Jie Wang, Wenxian Zhu, Xiangyu Yu, Zhaofei Wang, Jingjiao Ma, Hengan Wang, Yaxian Yan, Jianhe Sun, Yuqiang Cheng
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Immunology
Subjects:
chicken
dsRNA sensor
DDX1
IRF7
IFN-β
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.742074/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.742074/full

Similar Items