Ebselen oxide and derivatives are new allosteric HER2 inhibitors for HER2‐positive cancers
Human epidermal growth factor receptor 2 (ErbB2/HER2) is a tyrosine kinase receptor that is overexpressed in 25% of primary human breast cancers, as well as in multiple other cancers. HER2‐targeted therapies improved progression‐free and overall survival in patients with HER2+ breast cancers. Howeve...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2023-10-01
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Series: | Molecular Oncology |
Subjects: | |
Online Access: | https://doi.org/10.1002/1878-0261.13419 |