Structural and Functional Analysis of the Only Two Pyridoxal 5′-Phosphate-Dependent Fold Type IV Transaminases in <i>Bacillus altitudinis</i> W3

Structural and Functional Analysis of the Only Two Pyridoxal 5′-Phosphate-Dependent Fold Type IV Transaminases in <i>Bacillus altitudinis</i> W3

Aminotransferases are employed as industrial biocatalysts to produce chiral amines with high enantioselectivity and yield. BpTA-1 and BpTA-2 are the only two pyridoxal 5′-phosphate-dependent fold type IV transaminase enzymes in <i>Bacillus altitudinis</i> W3. Herein, we compared the stru...

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Bibliographic Details
Main Authors: Lixin Zhai, Zihao Xie, Qiaopeng Tian, Zhengbing Guan, Yujie Cai, Xiangru Liao
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Catalysts
Subjects:
aminotransferase
pyridoxal 5′-phosphate
secondary structure
conserved domain
AFM
catalytic activity
Online Access:https://www.mdpi.com/2073-4344/10/11/1308

Internet

https://www.mdpi.com/2073-4344/10/11/1308

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