Magnetite nanoparticles as a kinetically favorable source of iron to enhance GBM response to chemoradiosensitization with pharmacological ascorbate

Magnetite nanoparticles as a kinetically favorable source of iron to enhance GBM response to chemoradiosensitization with pharmacological ascorbate

Ferumoxytol (FMX) is an FDA-approved magnetite (Fe3O4) nanoparticle used to treat iron deficiency anemia that can also be used as an MR imaging agent in patients that can't receive gadolinium. Pharmacological ascorbate (P-AscH-; IV delivery; plasma levels ≈ 20 mM) has shown promise as an adjuva...

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Bibliographic Details
Main Authors: M.S. Petronek, N. Teferi, J.M. Caster, J.M. Stolwijk, A. Zaher, J.M. Buatti, D. Hasan, E.I. Wafa, A.K. Salem, E.G. Gillan, J.J. St – Aubin, G.R. Buettner, D.R. Spitz, V.A. Magnotta, B.G. Allen
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Redox Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231723000526

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http://www.sciencedirect.com/science/article/pii/S2213231723000526

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