Vascular leakage caused by loss of Akt1 is associated with impaired mural cell coverage

Vascular leakage caused by loss of Akt1 is associated with impaired mural cell coverage

Angiogenesis plays a critical role in embryo development, tissue repair, tumor growth and wound healing. In the present study, we investigated the role of the serine/threonine kinase Akt in angiogenesis. Silencing of Akt1 in human umbilical vein endothelial cells significantly inhibited vascular end...

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Bibliographic Details
Main Authors: Jung Min Ha, Seo Yeon Jin, Hye Sun Lee, Farzaneh Vafaeinik, Yoo Jin Jung, Hye Jin Keum, Sang Heon Song, Dong Hyung Lee, Chi Dae Kim, Sun Sik Bae
Format: Article
Language:English
Published: Wiley 2019-04-01
Series:FEBS Open Bio
Subjects:
Akt
angiogenesis
coverage
endothelium
mural cell
vascular leakage
Online Access:https://doi.org/10.1002/2211-5463.12621

Internet

https://doi.org/10.1002/2211-5463.12621

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