The molecular appearance of native TRPM7 channel complexes identified by high-resolution proteomics

The molecular appearance of native TRPM7 channel complexes identified by high-resolution proteomics

The transient receptor potential melastatin-subfamily member 7 (TRPM7) is a ubiquitously expressed membrane protein consisting of ion channel and protein kinase domains. TRPM7 plays a fundamental role in the cellular uptake of divalent cations such as Zn2+, Mg2+, and Ca2+, and thus shapes cellular e...

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Bibliographic Details
Main Authors: Astrid Kollewe, Vladimir Chubanov, Fong Tsuen Tseung, Leonor Correia, Eva Schmidt, Anna Rössig, Susanna Zierler, Alexander Haupt, Catrin Swantje Müller, Wolfgang Bildl, Uwe Schulte, Annette Nicke, Bernd Fakler, Thomas Gudermann
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-11-01
Series:eLife
Subjects:
brain
proteome
TRPM7 complexes
mouse
human
Xenopus
Online Access:https://elifesciences.org/articles/68544

Internet

https://elifesciences.org/articles/68544

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