Molecular and serological characterization of hepatitis B vaccine breakthrough infections in serial samples from two plasma donors

Molecular and serological characterization of hepatitis B vaccine breakthrough infections in serial samples from two plasma donors

Abstract Background Although vaccines for hepatitis B virus (HBV) are highly effective, HBV infections in vaccinees occur. Index samples of breakthrough infections are typically anti-HBc negative but HBV DNA positive with protective anti-HBs levels while HBsAg detection may be delayed or absent. HBs...

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Bibliographic Details
Main Authors: Mary C. Kuhns, Anne L. McNamara, Vera Holzmayer, Gavin A. Cloherty
Format: Article
Language:English
Published: BMC 2019-04-01
Series:Virology Journal
Subjects:
Hepatitis B virus
Hepatitis B surface antigen
Vaccine breakthrough
Hepatitis B surface antigen mutations
Online Access:http://link.springer.com/article/10.1186/s12985-019-1154-4

Internet

http://link.springer.com/article/10.1186/s12985-019-1154-4

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