Mechanism of autophagy induced by activation of the AMPK/ERK/mTOR signaling pathway after TRIM22-mediated DENV-2 infection of HUVECs

Mechanism of autophagy induced by activation of the AMPK/ERK/mTOR signaling pathway after TRIM22-mediated DENV-2 infection of HUVECs

Abstract Background Dengue virus type 2 (DENV-2) was used to infect primary human umbilical vein endothelial cells (HUVECs) to examine autophagy induced by activation of the adenosine monophosphate-activated protein kinase (AMPK)/extracellular signal-regulated kinase (ERK)/mammalian target of rapamy...

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Bibliographic Details
Main Authors: Ning Wu, Xiaoqin Gou, Pan Hu, Yao Chen, Jinzhong Ji, Yuanying Wang, Li Zuo
Format: Article
Language:English
Published: BMC 2022-12-01
Series:Virology Journal
Subjects:
DENV-2
Autophagy
AMPK/ERK/mTOR signaling pathway
TRIM22
Online Access:https://doi.org/10.1186/s12985-022-01932-w

Internet

https://doi.org/10.1186/s12985-022-01932-w

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