Image-based consensus molecular subtyping in rectal cancer biopsies and response to neoadjuvant chemoradiotherapy

Abstract The development of deep learning (DL) models to predict the consensus molecular subtypes (CMS) from histopathology images (imCMS) is a promising and cost-effective strategy to support patient stratification. Here, we investigate whether imCMS calls generated from whole slide histopathology...

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Bibliographic Details
Main Authors: Maxime W. Lafarge, Enric Domingo, Korsuk Sirinukunwattana, Ruby Wood, Leslie Samuel, Graeme Murray, Susan D. Richman, Andrew Blake, David Sebag-Montefiore, Simon Gollins, Eckhard Klieser, Daniel Neureiter, Florian Huemer, Richard Greil, Philip Dunne, Philip Quirke, Lukas Weiss, Jens Rittscher, Tim Maughan, Viktor H. Koelzer
Format: Article
Language:English
Published: Nature Portfolio 2024-04-01
Series:npj Precision Oncology
Online Access:https://doi.org/10.1038/s41698-024-00580-3