The mevalonate pathway promotes the metastasis of osteosarcoma by regulating YAP1 activity via RhoA

Osteosarcoma is the most common malignant bone tumour, and the metastasis of osteosarcoma is an important cause of death. Evidence has shown that the mevalonate pathway is highly activated and is expected to be a new target for tumour therapy. In this study, we investigated the effect of mevalonate...

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Bibliographic Details
Main Authors: Xing Du, Yunsheng Ou, Muzi Zhang, Kai Li, Wei Huang, Dianming Jiang
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2022-05-01
Series:Genes and Diseases
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2352304220301409