The fate of hippocampal synapses depends on the sequence of plasticity-inducing events

The fate of hippocampal synapses depends on the sequence of plasticity-inducing events

Synapses change their strength in response to specific activity patterns. This functional plasticity is assumed to be the brain’s primary mechanism for information storage. We used optogenetic stimulation of rat hippocampal slice cultures to induce long-term potentiation (LTP), long-term depression...

Full description

Bibliographic Details
Main Authors: J Simon Wiegert, Mauro Pulin, Christine Elizabeth Gee, Thomas G Oertner
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-10-01
Series:eLife
Subjects:
dendritic spine
optogenetics
long-term plasticity
two-photon imaging
CA1
GCaMP6
Online Access:https://elifesciences.org/articles/39151

Internet

https://elifesciences.org/articles/39151

Similar Items