Fast and deep phosphoproteome analysis with the Orbitrap Astral mass spectrometer

Fast and deep phosphoproteome analysis with the Orbitrap Astral mass spectrometer

Abstract Owing to its roles in cellular signal transduction, protein phosphorylation plays critical roles in myriad cell processes. That said, detecting and quantifying protein phosphorylation has remained a challenge. We describe the use of a novel mass spectrometer (Orbitrap Astral) coupled with d...

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Bibliographic Details
Main Authors: Noah M. Lancaster, Pavel Sinitcyn, Patrick Forny, Trenton M. Peters-Clarke, Caroline Fecher, Andrew J. Smith, Evgenia Shishkova, Tabiwang N. Arrey, Anna Pashkova, Margaret Lea Robinson, Nicholas Arp, Jing Fan, Juli Hansen, Andrea Galmozzi, Lia R. Serrano, Julie Rojas, Audrey P. Gasch, Michael S. Westphall, Hamish Stewart, Christian Hock, Eugen Damoc, David J. Pagliarini, Vlad Zabrouskov, Joshua J. Coon
Format: Article
Language:English
Published: Nature Portfolio 2024-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-51274-0

Internet

https://doi.org/10.1038/s41467-024-51274-0

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