Prenatal Exposure to Δ9-Tetrahydrocannabinol Affects Hippocampus-Related Cognitive Functions in the Adolescent Rat Offspring: Focus on Specific Markers of Neuroplasticity

Prenatal Exposure to Δ9-Tetrahydrocannabinol Affects Hippocampus-Related Cognitive Functions in the Adolescent Rat Offspring: Focus on Specific Markers of Neuroplasticity

Previous evidence suggests that prenatal exposure to THC (pTHC) derails the neurodevelopmental trajectories towards a vulnerable phenotype for impaired emotional regulation and limbic memory. Here we aimed to investigate pTHC effect on hippocampus-related cognitive functions and markers of neuroplas...

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Bibliographic Details
Main Authors: Valentina Castelli, Gianluca Lavanco, Salvatore Feo, Cesare D’Amico, Vincenzo Micale, Martin Kuchar, Fulvio Plescia, Anna Brancato, Carla Cannizzaro
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Pharmaceutics
Subjects:
prenatal THC exposure
adolescent rat offspring
spatial learning and memory
hippocampal excitatory plasticity
CB1R expression
Online Access:https://www.mdpi.com/1999-4923/15/2/692

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https://www.mdpi.com/1999-4923/15/2/692

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