Ribosome structures to near-atomic resolution from thirty thousand cryo-EM particles

Although electron cryo-microscopy (cryo-EM) single-particle analysis has become an important tool for structural biology of large and flexible macro-molecular assemblies, the technique has not yet reached its full potential. Besides fundamental limits imposed by radiation damage, poor detectors and...

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Bibliographic Details
Main Authors: Xiao-chen Bai, Israel S Fernandez, Greg McMullan, Sjors HW Scheres
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2013-02-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/00461