Quantitative Approach to Single-Nucleotide Polymorphism Analysis Using MALDI-TOF Mass Spectrometry

Pooling of DNA samples before genotyping is a valuable means of streamlining large-scale genotyping efforts in disease association studies, single-nucleotide polymorphism (SNP) validation or mutant allele screening programs. In this report, we explore the application of matrix-assisted laser desorpt...

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Bibliographic Details
Main Authors: Philip Ross, Laura Hall, Lawrence A. Haff
Format: Article
Language:English
Published: Taylor & Francis Group 2000-09-01
Series:BioTechniques
Online Access:https://www.future-science.com/doi/10.2144/00293rr05