Sex differences in long-term kidney fibrosis following neonatal nephron loss during ongoing nephrogenesis

Sex differences in long-term kidney fibrosis following neonatal nephron loss during ongoing nephrogenesis

Abstract Background Clinical studies suggest that female sex plays a protective role in the development and progression of kidney disease. Recent experimental studies indicate that in male rats early nephron loss under ongoing nephrogenesis is accompanied by severe long-term sequelae. In humans, nep...

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Bibliographic Details
Main Authors: Carlos Menendez-Castro, Nada Cordasic, Fabian B. Fahlbusch, Joachim Woelfle, Karl F. Hilgers, Andrea Hartner
Format: Article
Language:English
Published: SpringerOpen 2023-08-01
Series:Molecular and Cellular Pediatrics
Subjects:
Sex differences
Kidney fibrosis
Neonatal nephron loss
Nephrogenesis
Neonatal uninephrectomy
Online Access:https://doi.org/10.1186/s40348-023-00164-4

Internet

https://doi.org/10.1186/s40348-023-00164-4

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