Structure—yeast α-glucosidase inhibitory activity relationship of 9-O-berberrubine carboxylates
Abstract Thirty-five 9-O-berberrubine carboxylate derivatives were synthesized and evaluated for yeast α-glucosidase inhibitory activity. All compounds demonstrated better inhibitory activities than the parent compounds berberine (BBR) and berberrubine (BBRB), and a positive control, acarbose. The s...
Main Authors: | , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-11-01
|
Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-023-45116-0 |