The mitochondrial‐derived lncRNA MDL1 mediates a mitochondria‐to‐nucleus retrograde regulation by inhibiting the nuclear translocation of p53

The mitochondrial‐derived lncRNA MDL1 mediates a mitochondria‐to‐nucleus retrograde regulation by inhibiting the nuclear translocation of p53

Abstract It has been clear that mitochondria are not just nucleus‐relying entities; instead, they also modulate nuclear events reversely. Long noncoding RNAs (lncRNAs) are classified into nuclear‐encoded and mitochondrial‐derived lncRNAs (nulncRNAs and mtlncRNAs, respectively). Relative to nulncRNAs...

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Bibliographic Details
Main Authors: Jia Li, Ruolin Bai, Weijia Yang, Hui Miao, Yu Li, Hongyuan Dai, Ling Li, Yongyun Zhao, Xu Song
Format: Article
Language:English
Published: Wiley 2022-06-01
Series:MedComm – Oncology
Subjects:
mitochondrial lncRNA
p53 translocation
retrograde
Online Access:https://doi.org/10.1002/mog2.15

Internet

https://doi.org/10.1002/mog2.15

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