Mycoplasma pneumoniae CARDS toxin exploits host cell endosomal acidic pH and vacuolar ATPase proton pump to execute its biological activities

Abstract Mycoplasma pneumoniae is the leading cause of bacterial community-acquired pneumonia among hospitalized children in the United States. It is also responsible for a spectrum of other respiratory tract disorders and extrapulmonary manifestations in children and adults. The main virulence fact...

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Bibliographic Details
Main Authors: Kumaraguruparan Ramasamy, Sowmya Balasubramanian, Alejandra Kirkpatrick, Daniel Szabo, Lavanya Pandranki, Joel B. Baseman, T. R. Kannan
Format: Article
Language:English
Published: Nature Portfolio 2021-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-90948-3