Progression of Postprandial Blood Plasma Phospholipids Following Acute Intake of Different Dairy Matrices: A Randomized Crossover Trial
Studies have indicated that the dairy matrix can affect postprandial responses of dairy products, but little is known about the effect on postprandial plasma phospholipid levels. This study investigated postprandial plasma phospholipid levels following consumption of four different dairy products th...
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MDPI AG
2021-07-01
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| Online Access: | https://www.mdpi.com/2218-1989/11/7/454 |
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| author | Rebekka Thøgersen Ida Emilie I. Lindahl Bekzod Khakimov Louise Kjølbæk Klaus Juhl Jensen Arne Astrup Marianne Hammershøj Anne Raben Hanne Christine Bertram |
| author_facet | Rebekka Thøgersen Ida Emilie I. Lindahl Bekzod Khakimov Louise Kjølbæk Klaus Juhl Jensen Arne Astrup Marianne Hammershøj Anne Raben Hanne Christine Bertram |
| author_sort | Rebekka Thøgersen |
| collection | DOAJ |
| description | Studies have indicated that the dairy matrix can affect postprandial responses of dairy products, but little is known about the effect on postprandial plasma phospholipid levels. This study investigated postprandial plasma phospholipid levels following consumption of four different dairy products that are similar in micro and macro nutrients, but different in texture and structure: cheddar cheese (Cheese), homogenized cheddar cheese (Hom. Cheese), micellar casein isolate with cream (MCI Drink) or a gel made from the MCI Drink (MCI Gel). The study was an acute randomized, crossover trial in human volunteers with four test days. Blood samples were collected during an 8 h postprandial period and the content of 53 plasma phospholipids was analysed using liquid chromatography-mass spectrometry (LC-MS). No meal–time interactions were revealed; however, for nine of the 53 phospholipids, a meal effect was found. Thus, the results indicated a lower plasma level of specific lyso-phosphatidylethanolamines (LPEs) and lyso-phosphatidylcholines (LPCs) following consumption of the MCI Gel compared to the MCI Drink and Hom. Cheese, which might be attributed to an effect of viscosity. However, further studies are needed in order to reveal more details on the effect of the dairy matrix on postprandial phospholipids. |
| first_indexed | 2024-03-10T09:32:04Z |
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| id | doaj.art-06aef5974ce54ffa98c634d7622c3267 |
| institution | Directory Open Access Journal |
| issn | 2218-1989 |
| language | English |
| last_indexed | 2024-03-10T09:32:04Z |
| publishDate | 2021-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Metabolites |
| spelling | doaj.art-06aef5974ce54ffa98c634d7622c32672023-11-22T04:22:59ZengMDPI AGMetabolites2218-19892021-07-0111745410.3390/metabo11070454Progression of Postprandial Blood Plasma Phospholipids Following Acute Intake of Different Dairy Matrices: A Randomized Crossover TrialRebekka Thøgersen0Ida Emilie I. Lindahl1Bekzod Khakimov2Louise Kjølbæk3Klaus Juhl Jensen4Arne Astrup5Marianne Hammershøj6Anne Raben7Hanne Christine Bertram8Department of Food Science, Aarhus University, Agro Food Park 48, DK-8200 Aarhus N, DenmarkDepartment of Food Science, Aarhus University, Agro Food Park 48, DK-8200 Aarhus N, DenmarkDepartment of Food Science, University of Copenhagen, DK-1958 Frederiksberg C, DenmarkDepartment of Nutrition, Exercise and Sports, University of Copenhagen, DK-1958 Frederiksberg C, DenmarkArla Foods Amba, DK-8200 Aarhus N, DenmarkDepartment of Nutrition, Exercise and Sports, University of Copenhagen, DK-1958 Frederiksberg C, DenmarkDepartment of Food Science, Aarhus University, Agro Food Park 48, DK-8200 Aarhus N, DenmarkDepartment of Nutrition, Exercise and Sports, University of Copenhagen, DK-1958 Frederiksberg C, DenmarkDepartment of Food Science, Aarhus University, Agro Food Park 48, DK-8200 Aarhus N, DenmarkStudies have indicated that the dairy matrix can affect postprandial responses of dairy products, but little is known about the effect on postprandial plasma phospholipid levels. This study investigated postprandial plasma phospholipid levels following consumption of four different dairy products that are similar in micro and macro nutrients, but different in texture and structure: cheddar cheese (Cheese), homogenized cheddar cheese (Hom. Cheese), micellar casein isolate with cream (MCI Drink) or a gel made from the MCI Drink (MCI Gel). The study was an acute randomized, crossover trial in human volunteers with four test days. Blood samples were collected during an 8 h postprandial period and the content of 53 plasma phospholipids was analysed using liquid chromatography-mass spectrometry (LC-MS). No meal–time interactions were revealed; however, for nine of the 53 phospholipids, a meal effect was found. Thus, the results indicated a lower plasma level of specific lyso-phosphatidylethanolamines (LPEs) and lyso-phosphatidylcholines (LPCs) following consumption of the MCI Gel compared to the MCI Drink and Hom. Cheese, which might be attributed to an effect of viscosity. However, further studies are needed in order to reveal more details on the effect of the dairy matrix on postprandial phospholipids.https://www.mdpi.com/2218-1989/11/7/454cheesecaseinphospholipidomicsfood structuremilk phospholipids |
| spellingShingle | Rebekka Thøgersen Ida Emilie I. Lindahl Bekzod Khakimov Louise Kjølbæk Klaus Juhl Jensen Arne Astrup Marianne Hammershøj Anne Raben Hanne Christine Bertram Progression of Postprandial Blood Plasma Phospholipids Following Acute Intake of Different Dairy Matrices: A Randomized Crossover Trial Metabolites cheese casein phospholipidomics food structure milk phospholipids |
| title | Progression of Postprandial Blood Plasma Phospholipids Following Acute Intake of Different Dairy Matrices: A Randomized Crossover Trial |
| title_full | Progression of Postprandial Blood Plasma Phospholipids Following Acute Intake of Different Dairy Matrices: A Randomized Crossover Trial |
| title_fullStr | Progression of Postprandial Blood Plasma Phospholipids Following Acute Intake of Different Dairy Matrices: A Randomized Crossover Trial |
| title_full_unstemmed | Progression of Postprandial Blood Plasma Phospholipids Following Acute Intake of Different Dairy Matrices: A Randomized Crossover Trial |
| title_short | Progression of Postprandial Blood Plasma Phospholipids Following Acute Intake of Different Dairy Matrices: A Randomized Crossover Trial |
| title_sort | progression of postprandial blood plasma phospholipids following acute intake of different dairy matrices a randomized crossover trial |
| topic | cheese casein phospholipidomics food structure milk phospholipids |
| url | https://www.mdpi.com/2218-1989/11/7/454 |
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