Molecular trade-offs in RNA ligases affected the modular emergence of complex ribozymes at the origin of life

In the RNA world hypothesis complex, self-replicating ribozymes were essential. For the emergence of an RNA world, less is known about the early processes that accounted for the formation of complex, long catalysts from small passively formed molecules. The functional role of small sequences has not...

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Bibliographic Details
Main Authors: Nisha Dhar, Marc S. Weinberg, Richard E. Michod, Pierre M. Durand
Format: Article
Language:English
Published: The Royal Society 2017-01-01
Series:Royal Society Open Science
Subjects:
Online Access:https://royalsocietypublishing.org/doi/pdf/10.1098/rsos.170376