Functional genomics highlights differential induction of antiviral pathways in the lungs of SARS-CoV-infected macaques.

The pathogenesis of severe acute respiratory syndrome coronavirus (SARS-CoV) is likely mediated by disproportional immune responses and the ability of the virus to circumvent innate immunity. Using functional genomics, we analyzed early host responses to SARS-CoV infection in the lungs of adolescent...

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Bibliographic Details
Main Authors: Anna de Lang, Tracey Baas, Thomas Teal, Lonneke M Leijten, Brandon Rain, Albert D Osterhaus, Bart L Haagmans, Michael G Katze
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-08-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.0030112