Outer Membrane Protein 25 of Brucella Activates Mitogen-Activated Protein Kinase Signal Pathway in Human Trophoblast Cells

Outer Membrane Protein 25 of Brucella Activates Mitogen-Activated Protein Kinase Signal Pathway in Human Trophoblast Cells

Outer membrane protein 25 (OMP25), a virulence factor from Brucella, plays an important role in maintaining the structural stability of Brucella. Mitogen-activated protein kinase (MAPK) signal pathway widely exists in eukaryotic cells. In this study, human trophoblast cell line HPT-8 and BALB/c mice...

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Bibliographic Details
Main Authors: Jing Zhang, Yu Zhang, Zhiqiang Li, Jing Liu, Xuehua Shao, Changxin Wu, Yong Wang, Kaisheng Wang, Tiansen Li, Laizhen Liu, Chuangfu Chen, Hui Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-12-01
Series:Frontiers in Veterinary Science
Subjects:
Brucella
2308ΔOmp25
mitogen-activated protein kinase
cytokines
HPT-8 cells
Online Access:http://journal.frontiersin.org/article/10.3389/fvets.2017.00197/full

Internet

http://journal.frontiersin.org/article/10.3389/fvets.2017.00197/full

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