The Absent in Melanoma 2-Like Receptor IFN-Inducible Protein 16 as an Inflammasome Regulator in Systemic Lupus Erythematosus: The Dark Side of Sensing Microbes

The Absent in Melanoma 2-Like Receptor IFN-Inducible Protein 16 as an Inflammasome Regulator in Systemic Lupus Erythematosus: The Dark Side of Sensing Microbes

Absent in melanoma 2 (AIM2)-like receptors (ALRs) are a newly characterized class of pathogen recognition receptors (PRRs) involved in cytosolic and nuclear pathogen DNA recognition. In recent years, two ALR family members, the interferon (IFN)-inducible protein 16 (IFI16) and AIM2, have been linked...

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Bibliographic Details
Main Authors: Valeria Caneparo, Santo Landolfo, Marisa Gariglio, Marco De Andrea
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Immunology
Subjects:
IFN-inducible protein 16
absent in melanoma 2 (AIM2)-like receptor
inflammasome
interferon
systemic lupus erythematosus
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01180/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.01180/full

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