Age-dependent contribution of intrinsic mechanisms to sinoatrial node function in humans

Age-dependent contribution of intrinsic mechanisms to sinoatrial node function in humans

Abstract Average beat interval (BI) and beat interval variability (BIV) are primarily determined by mutual entrainment between the autonomic-nervous system (ANS) and intrinsic mechanisms that govern sinoatrial node (SAN) cell function. While basal heart rate is not affected by age in humans, age-dep...

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Bibliographic Details
Main Authors: Ido Weiser-Bitoun, Hitoshi Mori, Taisuke Nabeshima, Naomichi Tanaka, Daisuke Kudo, Wataru Sasaki, Masataka Narita, Kazuhisa Matsumoto, Yoshifumi Ikeda, Takahide Arai, Shintaro Nakano, Naokata Sumitomo, Taka-aki Senbonmatsu, Kazuo Matsumoto, Ritsushi Kato, Christopher H. Morrell, Kenta Tsutsui, Yael Yaniv
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-45101-7

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https://doi.org/10.1038/s41598-023-45101-7

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