Age-dependent contribution of intrinsic mechanisms to sinoatrial node function in humans
Abstract Average beat interval (BI) and beat interval variability (BIV) are primarily determined by mutual entrainment between the autonomic-nervous system (ANS) and intrinsic mechanisms that govern sinoatrial node (SAN) cell function. While basal heart rate is not affected by age in humans, age-dep...
Main Authors: | Ido Weiser-Bitoun, Hitoshi Mori, Taisuke Nabeshima, Naomichi Tanaka, Daisuke Kudo, Wataru Sasaki, Masataka Narita, Kazuhisa Matsumoto, Yoshifumi Ikeda, Takahide Arai, Shintaro Nakano, Naokata Sumitomo, Taka-aki Senbonmatsu, Kazuo Matsumoto, Ritsushi Kato, Christopher H. Morrell, Kenta Tsutsui, Yael Yaniv |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-11-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-023-45101-7 |
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