Combined Effects of Lycopene and Metformin on Decreasing Oxidative Stress by Triggering Endogenous Antioxidant Defenses in Diet-Induced Obese Mice

Combined Effects of Lycopene and Metformin on Decreasing Oxidative Stress by Triggering Endogenous Antioxidant Defenses in Diet-Induced Obese Mice

Since lycopene has antioxidant activity, its combination with metformin may be useful to contrast diabetic complications related to oxidative stress. This study aimed to investigate the effects of metformin combined with lycopene on high-fat diet (HFD)-induced obese mice. Seventy-two C57BL-6J mice w...

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Bibliographic Details
Main Authors: Bruno Pereira Motta, Camila Graça Pinheiro, Ingrid Delbone Figueiredo, Felipe Nunes Cardoso, Juliana Oriel Oliveira, Rachel Temperani Amaral Machado, Patrícia Bento da Silva, Marlus Chorilli, Iguatemy Lourenço Brunetti, Amanda Martins Baviera
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Molecules
Subjects:
paraoxonase-1
carotenoids
advanced glycation end products
glycoxidative stress
metabolic memory
Online Access:https://www.mdpi.com/1420-3049/27/23/8503

Internet

https://www.mdpi.com/1420-3049/27/23/8503

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