Biologically Enhanced Genome-Wide Association Study Provides Further Evidence for Candidate Loci and Discovers Novel Loci That Influence Risk of Anterior Cruciate Ligament Rupture in a Dog Model

Biologically Enhanced Genome-Wide Association Study Provides Further Evidence for Candidate Loci and Discovers Novel Loci That Influence Risk of Anterior Cruciate Ligament Rupture in a Dog Model

Anterior cruciate ligament (ACL) rupture is a common condition that disproportionately affects young people, 50% of whom will develop knee osteoarthritis (OA) within 10 years of rupture. ACL rupture exhibits both hereditary and environmental risk factors, but the genetic basis of the disease remains...

Full description

Bibliographic Details
Main Authors: Lauren A. Baker, Mehdi Momen, Rachel McNally, Mark E. Berres, Emily E. Binversie, Susannah J. Sample, Peter Muir
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Genetics
Subjects:
ACL rupture
ACL
cruciate rupture
dog model
anterior cruciate ligament
cruciate ligament
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.593515/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2021.593515/full

Similar Items