Regulation of mitochondria-dynactin interaction and mitochondrial retrograde transport in axons

Mitochondrial transport in axons is critical for neural circuit health and function. While several proteins have been found that modulate bidirectional mitochondrial motility, factors that regulate unidirectional mitochondrial transport have been harder to identify. In a genetic screen, we found a z...

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Bibliographic Details
Main Authors: Catherine M Drerup, Amy L Herbert, Kelly R Monk, Alex V Nechiporuk
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-04-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/22234