Pathophysiologic and clinical implications of molecular profiles resultant from deletion 5q

Pathophysiologic and clinical implications of molecular profiles resultant from deletion 5q

Summary: Background: Haploinsufficiency (HI) resulting from deletion of the long arm of chromosome 5 [del(5q)] and the accompanied loss of heterozygosity are likely key pathogenic factors in del(5q) myeloid neoplasia (MN) although the consequences of del(5q) have not been yet clarified. Methods: He...

সম্পূর্ণ বিবরণ

গ্রন্থ-পঞ্জীর বিবরন
প্রধান লেখক: Vera Adema, Laura Palomo, Wencke Walter, Mar Mallo, Stephan Hutter, Thomas La Framboise, Leonor Arenillas, Manja Meggendorfer, Tomas Radivoyevitch, Blanca Xicoy, Andrea Pellagatti, Claudia Haferlach, Jacqueline Boultwood, Wolfgang Kern, Valeria Visconte, Mikkael Sekeres, John Barnard, Torsten Haferlach, Francesc Solé, Jaroslaw P. Maciejewski
বিন্যাস: প্রবন্ধ
ভাষা:English
প্রকাশিত: Elsevier 2022-06-01
মালা:EBioMedicine
বিষয়গুলি:
Myelodysplastic syndromes
5q deletion
Haploinsufficiency
TP53
CSNK1A1
অনলাইন ব্যবহার করুন:http://www.sciencedirect.com/science/article/pii/S2352396422002407

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http://www.sciencedirect.com/science/article/pii/S2352396422002407

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