Mitochondrial Genotoxicity of Hepatitis C Treatment among People Who Inject Drugs

Mitochondrial Genotoxicity of Hepatitis C Treatment among People Who Inject Drugs

Antiviral nucleoside analogues (ANA) are newly used therapeutics acting against the hepatitis C virus (HCV). This class of drug is well known to exhibit toxicity on mitochondrial DNA (mtDNA). People who inject drugs (PWID) are particularly affected by HCV infection and cumulated mitotoxic drug expos...

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Bibliographic Details
Main Authors: Mélusine Durand, Nicolas Nagot, Quynh Bach Thi Nhu, Roselyne Vallo, Linh Le Thi Thuy, Huong Thi Duong, Binh Nguyen Thanh, Delphine Rapoud, Catherine Quillet, Hong Thi Tran, Laurent Michel, Thanh Nham Thi Tuyet, Oanh Khuat Thi Hai, Vinh Vu Hai, Jonathan Feelemyer, Philippe Vande Perre, Don Des Jarlais, Khue Pham Minh, Didier Laureillard, Jean-Pierre Molès
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Journal of Clinical Medicine
Subjects:
mitochondria
genotoxicity
HCV treatment
drug users
Online Access:https://www.mdpi.com/2077-0383/10/21/4824

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https://www.mdpi.com/2077-0383/10/21/4824

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