Supralinear Dependence of the IP Receptor-to-Mitochondria Local Ca Transfer on the Endoplasmic Reticulum Ca Loading
Calcium signal propagation from endoplasmic reticulum (ER) to mitochondria regulates a multitude of mitochondrial and cell functions, including oxidative ATP production and cell fate decisions. Ca 2+ transfer is optimal at the ER-mitochondrial contacts, where inositol 1,4,5-trisphosphate (IP 3 ) rec...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2024-02-01
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| Series: | Contact |
| Online Access: | https://doi.org/10.1177/25152564241229273 |