A Combination of CD28 (rs1980422) and IRF5 (rs10488631) Polymorphisms Is Associated with Seropositivity in Rheumatoid Arthritis: A Case Control Study.

A Combination of CD28 (rs1980422) and IRF5 (rs10488631) Polymorphisms Is Associated with Seropositivity in Rheumatoid Arthritis: A Case Control Study.

INTRODUCTION:The aim of the study was to analyse genetic architecture of RA by utilizing multiparametric statistical methods such as linear discriminant analysis (LDA) and redundancy analysis (RDA). METHODS:A total of 1393 volunteers, 499 patients with RA and 894 healthy controls were included in th...

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Main Authors: Lucia Vernerova, Frantisek Spoutil, Miroslav Vlcek, Katarina Krskova, Adela Penesova, Milada Meskova, Andrea Marko, Katarina Raslova, Branislav Vohnout, Jozef Rovensky, Zdenko Killinger, Ivana Jochmanova, Ivica Lazurova, Guenter Steiner, Josef Smolen, Richard Imrich
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4836711?pdf=render

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http://europepmc.org/articles/PMC4836711?pdf=render

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