In Silico Exploration of Microtubule Agent Griseofulvin and Its Derivatives Interactions with Different Human β-Tubulin Isotypes
Tubulin isotypes are known to regulate microtubule stability and dynamics, as well as to play a role in the development of resistance to microtubule-targeted cancer drugs. Griseofulvin is known to disrupt cell microtubule dynamics and cause cell death in cancer cells through binding to tubulin prote...
প্রধান লেখক: | , , , , |
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বিন্যাস: | প্রবন্ধ |
ভাষা: | English |
প্রকাশিত: |
MDPI AG
2023-03-01
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মালা: | Molecules |
বিষয়গুলি: | |
অনলাইন ব্যবহার করুন: | https://www.mdpi.com/1420-3049/28/5/2384 |